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Mixed Agonist/Antagonist and Partial Agonist Opioid Analgesics The concomitant usage of opioids with other opioid analgesics, for instance butorphanol, nalbuphine, pentazocine, might decrease the analgesic effect of oxycodone and acetaminophen tablets and/or precipitate withdrawal signs or symptoms. Advise client to stay away from concomitant use o